Current trends in modern pharmaceutical analysis for drug discovery.

A Review on Current Industrial Trends for Synthesis of Medicinal Compounds

In the pharmaceutical industry, computational methods have gained a major role in the discovery and development of new drugs. Yet, synthesis of the pharmaceutical compounds is among the most crucial steps of drug design along with the life science discoveries complementing it. The review focuses on all the recent developments in the application of computational methods as well as organic synthe...

Drug discovery in pharmaceutical industry: productivity challenges and trends.

Low productivity, rising R&D costs, dissipating proprietary products and dwindling pipelines are driving the pharmaceutical industry to unprecedented challenges and scrutiny. In this article I reflect on the current status of the pharmaceutical industry and reasons for continued low productivity. An emerging 'symbiotic model of innovation', that addresses underlying issues in drug failure and a...

A role for physicians in ethnopharmacology and drug discovery.

Ethnopharmacology investigations classically involved traditional healers, botanists, anthropologists, chemists and pharmacologists. The role of some groups of researchers but not of physician has been highlighted and well defined in ethnopharmacological investigations. Historical data shows that discovery of several important modern drugs of herbal origin owe to the medical knowledge and clini...

***Removed from the Issue*** Application of Cell-Based Assay Systems for the Early Screening of Human Drug Hepatotoxicity in the Discovery Phase of Drug Development

Withdrawing of Article ''Application of Cell-Based Assay Systems for the Early Screening of Human Drug Hepatotoxicity in the Discovery Phase of Drug Development''